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First Trust NYSE Arca Biotechnology ETF (FBT) and First Trust AlphaDEX U.S. Health Care Sector Index ETF (FHH.F) offer distinct profiles for Canadian ETF investors. A direct comparison shows that FBT focuses its top 3 sector exposures on Healthcare, while FHH.F leans towards Healthcare. When evaluating costs, FBT features a management fee (MER) of 0.15%, compared to 0.7% for FHH.F. Performance-wise, FBT has returned 37.78% year-to-date with +$5 M in net flows, whereas FHH.F is at 17.96% with -$0 M. Use the comparison tool below to benchmark these funds across top 10 holdings, yield, sector weights and historical returns.
NAV Performance and Flows
Key Data
Compare
FBT
FHH.F
| AuM | $8.36 M | $3.51 M |
| Management Fees | 0.15% | 0.70% |
| Exp. ratio | 0.71% | 0.76% |
| Tracking Difference | - | - |
Historical performance and flows
As of October 28, 2026
| 1M | 3M | YTD | 1Y | 3Y | ||
|---|---|---|---|---|---|---|
| Perf. | FBT | +0.92% | +10.24% | +37.78% | +47.46% | +113.62% |
FHH.F | +3.03% | +5.75% | +17.96% | +18.68% | +45.44% | |
| Flows | FBT | +$0 M | +$1 M | +$5 M | +$4 M | +$4 M |
FHH.F | +$0 M | +$0 M | -$0 M | +$0 M | +$0 M |
FBT vs FHH.F exposure
Countries
FBT
USA
82.68%
Other
17.32%
FHH.F
USA
93.13%
Sectors
FBT
Healthcare
99.86%
FHH.F
Healthcare
98.23%
As of October 28, 2026
Top 10 Holdings
FBT
Halozyme Therapeutics, Inc.
4.38%
Regeneron Pharmaceuticals, Inc.
3.84%
NeoGenomics, Inc.
3.83%
Corcept Therapeutics, Inc.
3.82%
Amgen, Inc.
3.74%
BeOne Medicines Ltd.
3.72%
Natera, Inc.
3.68%
Repligen Corp.
3.65%
argenx SE
3.63%
Gilead Sciences, Inc.
3.58%
FHH.F
Regeneron Pharmaceuticals, Inc.
2.86%
Pfizer Inc.
2.56%
Natera, Inc.
2.55%
Solventum Corp.
2.55%
Zimmer Biomet Holdings, Inc.
2.49%
Universal Health Services, Inc.
2.48%
Boston Scientific Corp.
2.43%
Guardant Health, Inc.
2.37%
Tenet Healthcare Corp.
2.29%
The Cigna Group
2.22%
Diversification
FBT
Total weight of top 10 holdings out of 30 total
37.87%
FHH.F
Total weight of top 10 holdings out of 72 total
24.80%
Characteristics
Compare
FBT
FHH.F
| Provider | First Trust | First Trust |
| Management | Passively managed | Passively managed |
| Benchmark | NYSE Arca Biotechnology Total Return Index - USD | StrataQuant Health Care Index - USD |
| Replication Method | Other | Direct (Physical) |
| Asset Class | Equity | Equity |
| Dividend Policy | Distributing | Distributing |
| Trailing 12m distribution yield | 0.00% | 0.46% |
| Meets ESG criteria | No | No |
| Inception Date | October 30, 2014 | December 7, 2017 |
Frequently asked questions about FBT and FHH.F
Which ETF has performed better year to date: FBT or FHH.F?
As of October 28, 2026, FBT has returned 37.78% year to date, while FHH.F has returned 17.96%. FBT is ahead on YTD performance.
Which ETF is larger by assets under management: FBT or FHH.F?
As of October 28, 2026, FBT manages $8.36 M in assets, while FHH.F manages $3.51 M. FBT is the larger fund by AUM.
How are FBT and FHH.F managed?
FBT is passively managed by First Trust. It tracks the NYSE Arca Biotechnology Total Return Index - USD benchmark. FHH.F is passively managed by First Trust. It tracks the StrataQuant Health Care Index - USD benchmark.
What sectors do FBT and FHH.F emphasize?
FBT is most exposed to Healthcare. FHH.F is most exposed to Healthcare.
Which ETF is attracting more investor flows: FBT or FHH.F?
Year to date, FBT has seen +$4.83 M in net flows, compared with -$0.00 M for FHH.F. FBT has attracted more net investor money so far.
How do the fees of FBT and FHH.F compare?
FBT has an expense ratio of 0.71%, while FHH.F has an expense ratio of 0.76%.
What are the top holdings of FBT and FHH.F?
FBT's largest holdings include Halozyme Therapeutics, Inc., Regeneron Pharmaceuticals, Inc., and NeoGenomics, Inc.. FHH.F's top holdings include Regeneron Pharmaceuticals, Inc., Pfizer Inc., and Natera, Inc..
Which ETF is more diversified: FBT or FHH.F?
FBT holds 30 securities, while FHH.F holds 72. On holdings count, FHH.F is the more diversified portfolio.
Recent articles about FBT and FHH.F
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All content on the ETF Market Canada is for your general information use only, Cboe is not responsible for any use of content by you outside this scope. In particular, the content does not constitute any form of advice, recommendation, representation, endorsement or arrangement by Cboe and is not intended to be relied upon by users in making (or refraining from making) any specific investment or other decisions.




